| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5228702 | Tetrahedron | 2008 | 6 Pages |
Abstract
An efficient copper-catalyzed N-arylation and N-heteroarylation reactions of imidazole, pyrrole, indole, pyrazole, and perimidine with aryl or heteroaryl halides using pyridine-functionalized 1,3-diketone as ligands have been investigated. The ligands bearing pyridyl and 1,3-diketone moieties, which may form chelated Cu(I) species, are inexpensive and readily available. The combination of CuI and 1,3-di(pyridine-2-yl)propane-1,3-dione is very efficient for C-N coupling reactions to afford various N-arylated products in good to excellent yields.
Keywords
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhenxing Xi, Fenghui Liu, Yongbo Zhou, Wanzhi Chen,