| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5228779 | Tetrahedron | 2007 | 6 Pages |
Abstract
A flexible method for the synthesis of 5,6-disubstituted furo[2,3-d]pyrimidine derivatives is described. The key step is a palladium-catalyzed arylative cyclization of alkynylpyrimidinols with various aryl iodides, which gave the title compounds in 36-75% yield.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Synthesis of novel 5,6-substituted furo[2,3-d]pyrimidines via Pd-catalyzed cyclization of alkynylpyrimidinols with aryl iodides](/preview/png/5228779.png "First Page Preview: Synthesis of novel 5,6-substituted furo[2,3-d]pyrimidines via Pd-catalyzed cyclization of alkynylpyrimidinols with aryl iodides")
Authors
Zhende Liu, Dewen Li, Shukun Li, Donglu Bai, Xuchang He, Youhong Hu,