Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5229078 | Tetrahedron | 2008 | 8 Pages |
Abstract
Hydrolysis of gem-dibromomethylarenes bearing carboxylate or boronate group to corresponding aldehydes without affecting the ester group was successfully accomplished in high yields by subjecting them to refluxing pyridine. Both aromatic and heteroaromatic substrates gave the corresponding aldehydes in good yields. This method was efficiently adapted for the large scale synthesis of 2d and 2f.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
John Kallikat Augustine, Y. Arthoba Naik, Ashis Baran Mandal, Nagaraja Chowdappa, Vinuthan B. Praveen,