Article ID Journal Published Year Pages File Type
5229104 Tetrahedron 2008 11 Pages PDF
Abstract
Guided by protein structure similarity clustering (PSSC), a 483-member compound library was synthesized based on the decalin core moiety of the naturally occurring Cdc25A (red) inhibitor dysidiolide 1 as 'leitmotif' yielding novel acetylcholinesterase (AChE, blue) inhibitors.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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