Article ID Journal Published Year Pages File Type
5229146 Tetrahedron 2007 7 Pages PDF
Abstract

The insecticidal tetrahydroisocoumarin, (3R,4S,4aR)-4,8-dihydroxy-3-methyl-3,4,4a,5-tetrahydro-1H-2-benzopyran-1-one, was synthesized as a racemate and as an optically active form using one-pot esterification-Michael addition-aldol reaction of δ-hydroxy-α,β-unsaturated aldehyde and diketene as a key step.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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