Article ID Journal Published Year Pages File Type
52292 Catalysis Communications 2007 4 Pages PDF
Abstract

An efficient synthesis of dihydropyrimidinones from the aldehyde, 1,3-dicarbonyl compound and urea (thiourea) under solvent-free conditions, using fluoroboric acid as the catalyst, is described. Compared with the classical Biginelli reaction conditions, this new protocol has the advantage of high yields, short reaction time and simplicity in the experimental procedure.

Related Topics
Physical Sciences and Engineering Chemical Engineering Catalysis
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