| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5229476 | Tetrahedron | 2006 | 29 Pages |
Abstract
The concept, protocols, instruments of fluorous solid-phase extraction techniques, and their applications for solution-phase parallel and high-throughput synthesis of small molecules and biomolecules are reviewed in this article.
Keywords
trimethylsilylTMSTFADBADCCFTiHOBtTHPBOCDcTFC-72HOAttert-butyloxycarbonylDMFDPPPBenzotrifluorideFluorous silica gelDppfdicyclohexylcarbodiimidemethoxymethylBTFRFHBINAPHFE-7100m-CPBA4-dimethylaminopyridineTPPμwLLETHF2-Chloro-4,6-dimethoxy-1,3,5-triazineReactantsCbzCDMTPerfluoroalkyl groupDMAPDBUTLC1-hydroxybenzotriazole1-hydroxy-7-azabenzotriazole1,8-Diazabicyclo[5.4.0]undec-7-eneDMSON-iodosuccinimideNiSN,N-dimethylformamideFluorous solid-phase extractionTrifluoroacetic acidOxonebenzyloxycarbonylBINOLTetrahydrofuranScavengerstriethylamineTriphenylphosphineSeparationLiquid–liquid separationdiethyl azodicarboxylatediisopropylethylamineDibenzylideneacetoneDimethylsulfoxideHigh-throughput synthesisSolution-phase synthesisParallel synthesisFluorousMoMmicrowaveDEADDIPEAReagentsPotassium peroxymonosulfateTEACatalystshigh-performance liquid chromatographyHPLCthin-layer chromatographyChiral auxiliariesProtecting groups
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Wei Zhang, Dennis P. Curran,