Article ID Journal Published Year Pages File Type
5229626 Tetrahedron 2007 6 Pages PDF
Abstract

The reaction of cyclohexyl isocyanide with various aldehydes and 1,3-dicarbonyl compounds catalyzed by piperidine is described. The protocol offers facile and efficient synthesis of 5-hydroxy-2H-pyrrol-2-one derivatives from readily available starting materials in high yields.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry