| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5229834 | Tetrahedron | 2007 | 5 Pages |
Abstract
A tandem cross-coupling reaction of aryl methyl ketones with aromatic aldehydes has been accomplished employing barium isopropoxide as a catalyst, in which barium enolates are generated and then three consecutive reactions (aldol reaction/β-elimination/conjugate addition) occur; this one-pot procedure is a convenient method to obtain symmetrical 1,5-diketones in good yields. In some cases, addition of iso-propanol is effective in improving the chemical yield.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Akira Yanagisawa, Hiroshi Takahashi, Takayoshi Arai,