Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5230706 | Tetrahedron | 2007 | 6 Pages |
Abstract
Acylphosphonates, which are easily available from carboxylic acids, are potent acyl anion precursors and undergo cyanide ion promoted phosphonate-phosphate rearrangement to provide the corresponding acyl anion equivalents as reactive intermediates. The protonation of these acyl anion equivalents furnished cyanohydrin O-phosphates in good yields. For the high yield formation of cyanohydrin O-phosphates from arylphosphonates THF should be used and from alkylphosphonates DME was used.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ayhan S. Demir, Ãmer Reis, Ilker Esiringü, Barbaros Reis, Sehriban Baris,