Recent approaches to the construction of 1-azaspiro[4.5]decanes and related 1-azaspirocycles

Article ID	Journal	Published Year	Pages	File Type
5231598	Tetrahedron	2006	26 Pages	PDF

Abstract

A variety of recently disclosed synthetic methods used to comstruct 1-azaspirocycles are presented.

Keywords

Spirocycles NBS NMO BOC trimethylsilyl AIBN PMB N-bromosuccinimide DPPA TMG DIB t-butoxycarbonyl DBB N-chlorosuccinimide methoxymethyl Tetramethylguanidine TBDPS TPAP Diphenylphosphorylazide TMS tetrapropylammonium perruthenate p-methoxybenzyl t-butyldimethylsilyl p-toluenesulfonyl TOL DMAP DBU HMDS TBAF Cbz TBS 4-dimethylaminopyridine TFA NCS THF Cyclohexyl DMSO NPs aryl ethyl Acetyl Trifluoroacetic acid Benzyl benzyloxycarbonyl butyl Tetrabutylammonium fluoride Tetrahydrofuran LDA Trifluoromethanesulfonate Room temperature Dimethylsulfoxide hours Molecular sieve phenyl MoM Methyl SEM Horner–Wadsworth–Emmons reaction Propyl

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

Recent approaches to the construction of 1-azaspiro[4.5]decanes and related 1-azaspirocycles

Authors

Gregory Dake,