| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5231742 | Tetrahedron | 2006 | 5 Pages |
Abstract
The first total synthesis of the alkaloid fumaramidine is reported. The synthetic tactics involve the sequential construction of the isoindolinone template by a Parham cyclization process followed by benzylic lactam deprotonation, interception with the suitable carboxaldehyde and ultimate E1cb elimination. Final N-lactam deprotection completes the synthesis of the Z configured title compound.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Marc Lamblin, Axel Couture, Eric Deniau, Pierre Grandclaudon,