Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5231882 | Tetrahedron | 2006 | 13 Pages |
Abstract
Prins cyclization reaction (PCR) of optically active homoallylic alcohols, RaC*H(OH)CH2CHCHCH3 (1-substituted but-2-en-1-ol), with aldehydes (RbCHO) in the presence of an acid-catalyst (HX) affords (2-Rb,3-CH3,4-X,6-Ra)-tetrasubstituted tetrahydropyrans highly stereoselectively in good yields.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kazuhide Kataoka, Yosuke Ode, Masashi Matsumoto, Junzo Nokami,