| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5232311 | Tetrahedron | 2006 | 9 Pages |
Abstract
Ï[(E)-CMeCH]- and Ï[(E)-CMeCMe]-type alkene isosteres are potential -CO-NH- and -CO-NMe-type peptide bond mimetics, respectively. The application of these chiral isosteres to conformational studies on cyclic RGD peptides having potent integrin antagonistic activities is reported.
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Authors
Shinya Oishi, Kazuhide Miyamoto, Ayumu Niida, Mikio Yamamoto, Keiichi Ajito, Hirokazu Tamamura, Akira Otaka, Yoshihiro Kuroda, Akira Asai, Nobutaka Fujii,