Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
52423 | Catalysis Communications | 2007 | 5 Pages |
Abstract
1,2-methylenedioxy-4(1-propenyl)benzene, isosafrol (1a), is an important intermediate for the synthesis of drugs like L-DOPA. In this work, different vanadium complexes have been evaluated as catalysts for the preparation of the corresponding double bond cleavage product, 3,4-methylenedioxybenzaldehyde, piperonal (2), and the corresponding epoxide, 2-methyl-3-[3′,4′-methylenedioxyphenyl]oxirane (3). When VCl2(salen) is used either with H2O2 60% or TBHP (5 M isooctane solution), the epoxide was the major product obtained in very good yields.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Heiddy Marquez Alvarez, Joyce L. de Andrade, Nei Pereira Jr., Estela M.F. Muri, Adolfo Horn Jr., Dayse Pereira Barbosa, O.A.C. Antunes,