| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5251997 | Tetrahedron | 2013 | 5 Pages |
Abstract
A mechanism for the reaction between rifamycin S and HS-CH2-CH(NH2)-R derivatives, leading to the formation of thiazole and thiazin-2-one rifamycin derivatives is proposed. It is shown that the ringcontraction thiazine thiazole occurs with extrusion of the CH2 group to the S atom, while the formation of the thiazole and the thiazin-2-one rifamycins depends on the nature of the R group.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Renato Cricchio,