| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5254166 | Tetrahedron | 2005 | 7 Pages |
Abstract
Cyclisations of carbinollactams 1b-3b afford macrocycles 4-6 in good yield by the intermediacy of N-acyliminium species. A similar process applied to lactams 21b-25b affords the pyrrolizidine type compounds 26-35 through consecutive azonium-Cope rearrangement and N-acyliminium ring closure. Additional results are concerned with the use of aromatic rings as Ï-nucleophiles.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
J.A.M. Hamersma, P.M.M. Nossin, W.N. Speckamp,