Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5254963 | Tetrahedron | 2009 | 13 Pages |
Abstract
These results allow to select the best 3-fluoropyridine-metallation conditions which lead to 3-fluoro-2-lithiopyridine on the one hand and to 3-fluoro-4-lithiopyridine on the other hand. Each of the lithiated isomers is then reacted with a great variety of electrophiles which gives very conveniently the corresponding 2,3- or 3,4-disubstituted pyridines.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Francis Marsais, Guy Queguiner,