Article ID Journal Published Year Pages File Type
5254963 Tetrahedron 2009 13 Pages PDF
Abstract
These results allow to select the best 3-fluoropyridine-metallation conditions which lead to 3-fluoro-2-lithiopyridine on the one hand and to 3-fluoro-4-lithiopyridine on the other hand. Each of the lithiated isomers is then reacted with a great variety of electrophiles which gives very conveniently the corresponding 2,3- or 3,4-disubstituted pyridines.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
, ,