| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5257052 | Tetrahedron | 2012 | 6 Pages |
Abstract
Carbonohydrazide and its thio-analogue undergo di-addition with ethoxycarbonyl isothiocyanate. The reaction terminates at the mono-addition stage when one of the hydrazine moieties of the (thio)carbonohydrazide is blocked. The resulting 6-(substiiuted)amino-1-ethoxycarbonyl-thiobiureas and bithioureas are cyclised to the appropriate 1-ethoxycarbonamido-1,3,4-thiadiazoles by acids, and to mercapto-1,2,4-triazoles by alkalis.
Related Topics
Physical Sciences and Engineering
Chemistry
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Authors
R. Esmail, F. Kurzer,