Article ID Journal Published Year Pages File Type
5258304 Tetrahedron Letters 2016 4 Pages PDF
Abstract
A highly regioselective and efficient metal-free hydration of aromatic haloalkynes to α-halomethyl ketones using cheap tetrafluoroboric acid as catalyst is described. The protocol is conducted under convenient conditions and affords products in good to excellent yields, with broad substrate scope, including a variety of aromatic alkynyl chlorides, alkynyl bromides, and alkynyl iodides.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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