Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5258304 | Tetrahedron Letters | 2016 | 4 Pages |
Abstract
A highly regioselective and efficient metal-free hydration of aromatic haloalkynes to α-halomethyl ketones using cheap tetrafluoroboric acid as catalyst is described. The protocol is conducted under convenient conditions and affords products in good to excellent yields, with broad substrate scope, including a variety of aromatic alkynyl chlorides, alkynyl bromides, and alkynyl iodides.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Min Ye, Yuelu Wen, Huifang Li, Yejuan Fu, Qinghao Wang,