| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5258972 | Tetrahedron Letters | 2016 | 6 Pages |
Abstract
A new organocatalytic approach to the synthesis of ceramide trafficking inhibitor HPA-12 has been described starting from phenacyl bromide. The strategy involves chiral CBS reduction of γ-ketoester and proline-catalyzed α-amination reaction of aldehyde followed by reduction as the key chirality inducing steps.86
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Authors
Komal G. Lalwani, Arumugam Sudalai,