Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5261000 | Tetrahedron Letters | 2014 | 5 Pages |
Abstract
Electron deficient purines can be reduced to 7,8-dihydropurines when treated with cheap and easy-to-handle sodium borohydride in methanol. The dihydropurine formed by reduction of tris-Boc-protected adenine is a useful intermediate in efficient syntheses of 7-alkyladenines and tetrahydro[1,4]diazepino[1,2,3-gh]purines.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Thomas Ihle Aarhus, Urs Fabian Fritze, Martin Hennum, Lise-Lotte Gundersen,