| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5261007 | Tetrahedron Letters | 2014 | 6 Pages |
Abstract
- We achieved the practical synthesis of Suvorexant.
- We synthesized Suvorexant in 10 steps with 31% overall yield.
- Synthetic route includes intramolecular Mitsunobu cyclization as a key step.
- Our work makes Suvorexant more accessible to researchers.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Daisuke Minehira, Satoyuki Takahara, Isao Adachi, Naoki Toyooka,