Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5261020 | Tetrahedron Letters | 2014 | 5 Pages |
Abstract
Nucleophilic addition of readily available TMSCCl3 to N-phosphinoyl benzaldimines allows preparation of N-phosphinoyl-α-(trichloromethyl)benzylamines. Typically, the reaction in THF at room temperature using tetrabutylammonium difluorotriphenylsilicate (TBAT) as a catalytic promoter, afforded very good yields (65-95% range) for most derivatives within 1 h at room temperature.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Benoit Wahl, Albert Cabré, Simon Woodward, William Lewis,