Synthesis and characterization of hydrophilic theophylline base compounds and their use as ligands in the microwave assisted Suzuki-Miyaura couplings of halopyridines in water

- New hydrosoluble theophylline derivatives were synthesized and characterized.
- Xanthine derivatives were successfully used in palladium catalyzed Suzuki-Miyaura couplings.
- The catalytic system proposed works efficiently under mild, greener conditions in water.
- The products obtained from the catalytic experiments are highly interesting in different areas of chemistry and industry.