Article ID Journal Published Year Pages File Type
5261204 Tetrahedron Letters 2014 4 Pages PDF
Abstract
We herein report a general N-alkylation reaction of lactams with secondary heterobenzylic bromides. This methodology features mild reaction condition, moderate to high product isolation yield, and broad substrate scope. Good chemical and structural tolerance has also been demonstrated by both the secondary heterobenzylic bromides and lactam substrates.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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