Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5261204 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
We herein report a general N-alkylation reaction of lactams with secondary heterobenzylic bromides. This methodology features mild reaction condition, moderate to high product isolation yield, and broad substrate scope. Good chemical and structural tolerance has also been demonstrated by both the secondary heterobenzylic bromides and lactam substrates.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ming Yu, Karis Stevenson, Gene Zhou,