| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5261211 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
An I2-promoted 3-formylation of free (N-H) and N-substituted indoles with tetramethylethylenediamine (TMEDA) and H2O as the carbonyl source is achieved, providing 3-formylindole in moderate to excellent yields with good functional group tolerance. This procedure represents an exceedingly attractive alternative to the traditional formylation methods.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Bo Zhang, Bin Liu, Jianbin Chen, Jiehui Wang, Miaochang Liu,