Article ID Journal Published Year Pages File Type
5261221 Tetrahedron Letters 2014 7 Pages PDF
Abstract
An efficient, three-component domino reaction of dimedone 1, aromatic aldehydes (2a-o), and 1,3-cyclohexanedione 1a in the regio-selective synthesis of 3,3-dimethyl-9-phenyl-2H-xanthene-1,8(5H,9H)-diones (3a-o) is reported. The desired product, 3 is efficiently promoted by ascorbic acid as an organo catalyst.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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