Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5261230 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
A versatile synthesis of symmetrically and unsymmetrically substituted thiopyrano[2,3-b:6,5-bâ²]diindoles has been developed by the condensation of 2-(alkylthio)-indole-3-carbaldehydes with indoline-2-thiones in the presence of catalytic amount of ethylenediamine diacetate (EDDA). The EDDA mediated condensation leads to a spontaneous cyclization followed by aromatization to form thiopyrano[2,3-b:6,5-bâ²]diindoles in quantitative yields.
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Authors
Mukund Jha, Michael Edmunds, Kate-lyn Lund, Ashley Ryan,