| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5261356 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
Treatment of nitroolefins and o-phenylenediamine with silica gel catalyst produced quinoxalines mainly in THF, but gave benzimidazoles efficiently in water. Such a solvent-dependent chemoselective reaction has prominent features of affording two cyclized products selectively with the same substrate, short reaction time, operational simplicity, as well as available starting materials and nontoxic catalysts. In addition, the scope and limitations were explored and a plausible reaction mechanism is proposed.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Chunmei Li, Furen Zhang, Zhen Yang, Chenze Qi,