Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5261371 | Tetrahedron Letters | 2014 | 14 Pages |
Abstract
Initial reaction of 3-aminopyrrole with the conjugate acid of 3,6-diphenyl-1,2,4,5-tetrazine gave an intermediate that rearranged to a 1H-1,2,4-(triazol-3-yl)pyrimidine via an unprecedented cascade. In this cascade, the s-tetrazine-ring opened, contracted to a 1,2,4-triazole-ring, and the pyrrole ring expanded to a pyrimidine. Similar results were obtained with three other electronically different s-tetrazines.
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Authors
Michael De Rosa, David Arnold, Hemant Yennawar,