Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5261376 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
The development of a calcium-mediated stereoselective reduction of α,β-epoxy ketones is reported. The corresponding α,β-epoxy alcohols are obtained in very good anti diastereoselectivity using Ca(OTf)2 and NaBH4. Furthermore, we have shown that our method can diastereoselectively reduce α,β-aziridinyl ketones.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Nina V. Forkel, David A. Henderson, Matthew J. Fuchter,