Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5261636 | Tetrahedron Letters | 2015 | 4 Pages |
Abstract
An efficient synthetic route to approach polysubstituted thiophene derivatives was achieved via the Et3N-mediated (Claisen) rearrangement reaction from α-oxo S-methyl-S-propargyl ketenes, followed by regioselective intramolecular cyclization. This method is very efficacious due to its environmental benignity, metal-free mediation, and high atom economy.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xiaoli Kan, Xiaobing Yang, Fangzhong Hu, Yang Wang, Ying Liu, Xiaomao Zou, Hengyu Li, Hao Li, Qichun Zhang,