Article ID Journal Published Year Pages File Type
5261636 Tetrahedron Letters 2015 4 Pages PDF
Abstract
An efficient synthetic route to approach polysubstituted thiophene derivatives was achieved via the Et3N-mediated (Claisen) rearrangement reaction from α-oxo S-methyl-S-propargyl ketenes, followed by regioselective intramolecular cyclization. This method is very efficacious due to its environmental benignity, metal-free mediation, and high atom economy.
Keywords
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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