A simple and facile method for regio- and stereoselective bromoformyloxylation and bromoacetoxylation of olefins using NH4Br and oxone®

A mild and efficient protocol for the preparation of bromoformates as well as bromoacetates from olefins using NH4Br and oxone® in nucleophile sources (DMF or DMA) without employing catalyst at room temperature is described. This method is facile, environmentally friendly and cost effective. A variety of terminal, internal and cyclic alkenes reacted smoothly to give the corresponding bromoformate and acetate products in good to excellent yields. Moreover, 1,2-disubstituted olefins provided moderate to excellent diastereoselectivity.