Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5262258 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
Michael addition of indoles to β-nitrostyrenes is reported using HY zeolite as catalyst under mild reaction conditions. This methodology allows the synthesis of various indole derivatives in good to high yields at 50 °C under solvent-free conditions. The short reaction time and achieving high yield of the desired products are the main advantages of the present work. The catalyst can be easily recovered and reused for six successive runs without considerable changes in yields. This Michael addition catalyzed by HY zeolite is operationally simple and can be considered as a greener protocol as it avoids the use of corrosive acids and toxic reagents.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mariappan Jeganathan, Kuppusamy Kanagaraj, Amarajothi Dhakshinamoorthy, Kasi Pitchumani,