Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5262481 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
A stereoselective total synthesis of the naturally occurring cytotoxic lactones (+)-boronolide, (+)-anamarine, and 8-epi-spicigerolide is described. d-Xylose has been used as a chiral source to construct the four contiguous oxygenated stereogenic centers of target molecules. The diastereoselective allylation was performed using Brown's protocol and the lactone moiety was prepared by ring closing metathesis.
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Authors
B.V. Subba Reddy, V. Veerabhadra Reddy, K. Praneeth,