Article ID Journal Published Year Pages File Type
5262647 Tetrahedron Letters 2015 5 Pages PDF
Abstract
A facile and highly efficient methodology was developed to synthesize the functional indene acetal through the cyclization of o-(alkynyl)styrene ether catalyzed by the Au(I) in the presence of MeOH. The 2-aryl-1H-indene acetals were obtained in excellent yields and could be easily transformed to indene aldehyde. Notably, the MeOH played a dual role, which includes acting as both a nucleophilic reagent and an auxiliary to mediate the cyclization of the 1,5-enyne ether.
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Physical Sciences and Engineering Chemistry Organic Chemistry
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