Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5262951 | Tetrahedron Letters | 2013 | 5 Pages |
Abstract
The identification and development of an aldehyde-bisulfite adduct as an isolable starting material in the synthesis of the CETP inhibitor Evacetrapib are described. The physical properties of the sodium and potassium analogs are compared, and the extension of the scope of this study to include an investigation into the solid state properties of a range of sodium and potassium bisulfite adducts of commonly encountered aldehydes is discussed.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Marie G. Kissane, Scott A. Frank, Gregory A. Rener, Christopher P. Ley, Charles A. Alt, Paul A. Stroud, Radhe K. Vaid, Sathish K. Boini, Laura A. McKee, Jeffrey T. Vicenzi, Gregory A. Stephenson,