Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5263152 | Tetrahedron Letters | 2014 | 5 Pages |
Abstract
Total synthesis of ent-diospongin A and epimer-diospongin B has been accomplished in good yield with high optical purity. The key steps of diospongin synthesis involve Julia-Kocienski olefination, Weinreb amide formation, Grignard reaction, reduction, acetonide deprotection, Lewis acid catalyzed cyclization, and Wacker oxidation.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Suresh Babu Meruva, Ramamohan Mekala, Akula Raghunadh, K. Raghavendra Rao, Vilas H. Dahanukar, T.V. Pratap, U.K. Syam Kumar, P.K. Dubey,