Article ID Journal Published Year Pages File Type
5263152 Tetrahedron Letters 2014 5 Pages PDF
Abstract
Total synthesis of ent-diospongin A and epimer-diospongin B has been accomplished in good yield with high optical purity. The key steps of diospongin synthesis involve Julia-Kocienski olefination, Weinreb amide formation, Grignard reaction, reduction, acetonide deprotection, Lewis acid catalyzed cyclization, and Wacker oxidation.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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