Article ID Journal Published Year Pages File Type
5263557 Tetrahedron Letters 2014 4 Pages PDF
Abstract
Acetamide/SO2Cl2 reagent has been developed for effective Friedel-Craft's acylation of aromatic compounds. Acylation of aromatic compounds with acetamide/SO2Cl2 was much more effective and faster than analogous (acetamide/SOCl2) and (acetamide/POCl3) reagents even under conventional conditions. However, microwave and ultrasonic assisted reactions afforded high yields of products in very short reaction times (30-40 min under sonication and 3-4 min under microwave assisted conditions).
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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