Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5263559 | Tetrahedron Letters | 2014 | 6 Pages |
Abstract
Benzopyran fused tetra and pentacyclic frameworks have been synthesized by the domino Knoevenagel hetero Diels-Alder (DKHDA) reaction using various 1,3-diones with O-allylated salicylaldehydes and O-propargylated salicylaldehydes in a solvent and catalyst free condition via Solid-State Melt Reaction (SSMR). The reaction requires only a single step operation thus providing potentially bioactive polycyclic heterocycles in high yields.
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Authors
Manickam Bakthadoss, Govindan Sivakumar,