Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5263752 | Tetrahedron Letters | 2013 | 11 Pages |
Abstract
An efficient one-pot method for the synthesis of 2-aminothiazoles using simple starting materials like isothiocyanates, amidines/guanidines and various halomethylenes is reported. The synthesis of 2-aminothiazoles involves reactions such as nucleophilic addition, S-alkylation and intramolecular nucleophilic substitution in which amines departs as the leaving group.
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Authors
Hitesh B. Jalani, Amit N. Pandya, Dhaivat H. Pandya, Jayesh A. Sharma, V. Sudarsanam, Kamala K. Vasu,