Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5263862 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
A highly organocatalytic asymmetric Michael addition of ethyl nitroacetate to enones by using C1-symmetric chiral primary-secondary diamines has been developed. In assistance of o-nitrobenzoic acid, chiral amine 1f which was derived from l-tryptophane and d-camphor can effectively promote the transformation in high yields (up to 96%) and enantioselectivities (up to 95%) under mild conditions.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yirong Zhou, Qiang Liu, Yuefa Gong,