Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5263895 | Tetrahedron Letters | 2014 | 6 Pages |
Abstract
A novel and efficient racemization catalyst, Pd/layered double-hydroxide-dodecyl sulfate anion, was prepared and used in the dynamic kinetic resolution (DKR) of arylamines. The undesired enantiomer was completely racemized at 55 °C, allowing the catalyst to be compatible with biocatalysts. DKR proceeded smoothly and showed a broad substrate scope, with good conversion and high product enantiomeric excesses (eep). The system could be reused more than 30 times without loss of conversion and eep value.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gang Xu, Xiaoting Dai, Simin Fu, Jianping Wu, Lirong Yang,