Article ID Journal Published Year Pages File Type
5263900 Tetrahedron Letters 2014 4 Pages PDF
Abstract
The intramolecular zinc bis-proline-phenol complex 2a was found to promote enantioselective iodolactonization reactions of both electron-rich and electron-poor 5-aryl-5-hexenoic acids affording δ-iodolactones in good chemical yields with up to 82% enantiomeric excess. The reactions were found to be insensitive to air and moisture, providing an experimentally simple protocol for synthetically useful compounds.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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