| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5263933 | Tetrahedron Letters | 2014 | 5 Pages |
Abstract
Pictet-Spengler reactions of oxetan-3-ones and azetidin-3-ones with tryptamine and tryptophan derivatives produce spirocyclic tetrahydro-β-carbolines in good yields. Molecular iodine (5 mol %) is an effective catalyst in most cases and high levels of diastereoselectivity are witnessed using 2-substituted oxetan-3-ones.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Benjamin O. Beasley, Abimbola Alli-Balogun, Guy J. Clarkson, Michael Shipman,