Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5263961 | Tetrahedron Letters | 2013 | 6 Pages |
Abstract
An imidazolidin-2-one chiral auxiliary mediated acetate aldol reaction was explored in the enantioselective synthesis of (S)-dapoxetine (SSRI). The diastereoselective aldol adduct was transformed to highly enantiopure (S)-dapoxetine with overall good yield.
Related Topics
Physical Sciences and Engineering
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Authors
Gopal L. Khatik, Ratnesh Sharma, Varun Kumar, Mangilal Chouhan, Vipin A. Nair,