| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5263978 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
A facile method of regioselective formylation of disubstituted benzene via in situ deprotonation/metalation using n-BuLi/TMEDA/DIPA has been developed. Effect of different electron withdrawing and electron donating substituents in 1,3-interrelated aromatic system was studied; the metalation mostly occurred at the 2-position to afford the desired products in high yields.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Le Wang, Yan Wang, Fangxu Guo, Yue Zheng, Pinaki S. Bhadury, Zhihua Sun,