| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5264086 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
An efficient ruthenium-catalyzed oxidative cyclization of enamides with alkynes in water or dimethoxyethane leading to the pyrrole derivatives is reported. Typically, a mixture of ethyl 2-(acetylamino)acrylate, diphenylacetylene, [Ru(p-cymene)Cl2] (2 mol %), KPF6, and Cu(OAc)2 in water was heated under refluxing conditions providing the N-acetylated pyrrole product in 95% yield.
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Authors
Kaliyappan Murugan, Shiuh-Tzung Liu,