Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5264116 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
Our investigation has shown that achiral quaternary ammonium salt has a significant synergistic effect on the asymmetric additions of diethylzinc to aldehydes catalyzed by chiral phosphoramide-Zn(II) complex. The addition of 10 mol % NBu4X can dramatically reduce the loading amount of chiral ligand without sacrificing the excellent reactivity and enantioselectivity of the asymmetric reaction.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hua Zong, Huayin Huang, Guangling Bian, Ling Song,